Our History

Apr. 1999 Founded in Hodogaya, Yokohama.
Apr. 1999 Started collaborative research with Hitachi Software Engineering Co., Ltd. [currently Hitachi, Ltd.].
Aug. 1999 Marketed the first made-in-Japan DNA chip “Yeast Chip ver. 1.0.”
Dec. 2001 Moved headquarter to Science Frontier District, Tsurumi-ku, Yokohama.
Seq. 2002 Started the new product “AceGene Human Oligo Chip 30K”.
Nov. 2002 Corporate name changed to DNA Chip Research Inc.
Jun. 2003 Split of 1 common stock into 2 shares.
Jun. 2003 Started the new product “Ace Gene Mouse Oligo Chip 30K”.
Mar. 2004 Announced IPO on Tokyo Stock Exchange MOTHERS (Capital increased to 600 million Japanese Yen).
Jun. 2004 Started the new product “Ace Gene 30K on One Chip Version”.
Seq. 2004 Started the new product “Hyper Gene Rat cDNA Chip”.
May. 2005 Split of 1 common stock into 2 shares.
Nov. 2005 Developed a new amination reagent and signed a license agreement with Sigma-Aldrich Japan.
Apr. 2006 Started the new product services “AceGene Premium Human”.
May. 2006 Started the new product “3D-Gene with Probe Bank”.
Jun. 2006 First issuance of convertible bonds: Issued the first series of unsecured convertible bonds with stock acquisition rights.
Nov. 2006 Formed strategic alliance on microarray business with Agilent Technologies Inc., USA.
Dec. 2006 Completed the full conversion of the first series of unsecured convertible bonds with stock acquisition rights into shares.
May. 2007 Started new product services “ConPath Chip” and “ConPath Navigator”.
Aug. 2007 Marketed “Hyb-Teacher”, an educational microarray genotyping kit for students.
Nov. 2007 Received 24th Industrial Technology Development Incentive Award from Kanagawa Prefecture for development of “Probe Bank”.
Mar. 2008 Transferred the Genome Analysis Department from HuBit Genomics Co., Ltd.
Mar. 2008 Started Clinical Trial using “RNA Check” to assess the efficacy of DMARD's (Disease Modifying Anti-Rheumatic Drugs).
Mar. 2008 Started service of “Mamma Print”, a risk assessment test on prognosis of Breast Cancer.
Apr. 2009 Accredited with Privacy Mark.
Jul. 2010 Formed strategic alliances with TAKEDA RIKA KOGYO Co., Ltd. and WaferGeneBiosystems, Inc.
Started the Exclusive Sales and Contract Service for the Next-Generation Ultra-High-Speed Ultra-High Sensitivity Real-Time PCR System (SmartChip) in Japan.
Jan. 2011 Formed a business alliance with RIKEN GENESIS Co., Ltd. for genetic analysis services.
Mar. 2011 Marketed “iCIS-crdb”, a gene expression data service for clinical research.
Apr. 2011 Marketed “iRIS”, a rheumatoid arthritis electronic survey system in clinical settings.
Dec. 2011 Marketed “TBONE EX KIT”, a DNA extraction kit for hard tissue such as tooth and bone.
Oct. 2013 Split of 1 common share into 100 shares and adoption of a unit stock system.
Oct. 2013 Formed strategic alliance with Agilent Technologies Inc., USA on Next Generation Sequence analysis service.
Aug. 2014 Transferred to the 2nd Section of the Tokyo Stock Exchange.
Nov. 2014 Signed capital and business alliance agreement with Enplas Corporation (Capital increased to 1.4 billion Japanese yen).
Mar. 2015 Original research paper published on identification of miRNA that regulates tumorigenesis of glioma, in collaboration with Ehime University Graduate School of Medicine and Hokkaido University.
Apr. 2015 Launched liquid biopsy companion diagnostic test DiVA-EGFR Check to detect rare mutants in plasma cell-free DNA of lung cancer patients.
Apr. 2015 Developed and published a set of external RNA standards and control probes, which enable multi-platform calibration and data validation among microarray, qPCR and NGS (part of a JMAC (Japan Multiplex bio-Analysis Consortium) project).
May. 2015 Patent awarded for Biomarker and Method used for Determining Rheumatoid Arthritis Disease Activity (Patent Number: 5676777).
Nov. 2015 Moved the research laboratory and office to Minato ward, Tokyo.
Jun. 2017 Transitioed from a company with a Board of Corporate Auditors to a company with an Audit and supervisory Committee.
May. 2020 Cancelled the capital and business alliance agreement with Enplas Corporation.
Nov. 2021 Formed a business alliance with Genemetrix LLC for the lung cancer compact panel business.
Oct. 2022 Established a medical laboratory in Kawasaki City, Kanagawa.
Jan. 2023 Signed a capital and business alliance agreement with Mitsui Chemicals, Inc.
Oct. 2024 Moved the laboratory to Kawasaki City, Kanagawa.
Apr. 2025 Mitsui Chemicals, Inc. concludes a public Takeover bid (TOB).
Jun. 2025 Stock consolidated through the Takeover bid (TOB).
Jun. 2025 Transitioned from a company with an Audit and Supervisory Committee to a company with a Board of Corporate Auditors.
Jun. 2025 Delisted on the Tokyo Stock Exchange, Standard Market
Became a corporate group company of Mitsui Chemicals, Inc.